研究論文リスト Publication list

2010年~

124.Yokokawa H, Higashino A, Suzuki S, Moriyama M, Nakamura N, Suzuki T, Suzuki R, Ishii K, Kobiyama K, Ishii K,  Wakita T, Akari H, Kato T: Induction of humoural and cellular immunity by immunisation with HCV particle vaccine in a non-human primate model. Gut. 2016 Oct 26. doi: 10.1136/gutjnl-2016-312208

 

123. Yoshida T, Takemoto H, Sakamaki T, Tokuyama N, Hart J, Hart T, Dupain J, Cobden A, Mulavwa M, Kawamoto Y, Kaneko A, Enomoto Y, Sato E, Kooriyama T, Miyabe-Nishiwaki T, Suzuki J, Saito A, Okamoto M, Tomonaga M, Matsuzawa T, Furuichi T, Akari H:  Epidemiological surveillance of lymphocryptovirus infection in wild bonobos. Frontiers in Microbiology 10, 3389, 2016.

 

122. Sugata K, Yasunaga J-i, Miura M, Akari H, Utsunomiya A, Nosaka K, Watanabe Y, Suzushima H, Koh KR, Nakagawa M, Kohara M, Matsuoka M: Enhancement of anti-STLV-1/HTLV-1 immune responses through multimodal effects of anti-CCR4 antibody. Scientific Reports 6, 27150, 2016.  


121. Sultana T, Nakayama EE, Tobita S, Yokoyama M, Seki Y, Saito A, Nomaguchi M, Adachi A, Akari H, Sato H, Shioda T: Novel mutant
human immunodeficiency virus type 1 strains with high degree of resistance to cynomolgus macaque TRIMCyp generated by random
mutagenesis. Journal of General Virology 97, 963-976, 2016.   

 

120. Suzuki S, Mori KI, Higashino A, Iwasaki Y, Yasutomi Y, Maki N, Akari H: Persistent replication of hepatitis C virus genotype 1b-based chimeric clone carrying E1, E2 and p6 regions from GB virus B in a New World monkey. Microbiology and Immunology 30, 26-34, 2016.

 

119. Nomura T, Yamamoto H, Ishii H, Akari H, Naruse TK, Kimura A, Matano T: Broadening of virus-specific CD8+ T-cell responses is indicative of residual viral replication in aviremic SIV controllers. PLoS Pathogens 11, e1005247, 2015.

 

118. Ma G, Yasunaga J-i, Akari H, Matsuoka M: TCF1 and LEF1 act as T-cell intrinsic HTLV-1 antagonists by targeting Tax. Proceedings of the National Academy of Sciences USA 112, 2216-2221, 2015.

 

117. Yoshida T, Akari H: Role of accessory proteins in primate immunopathogenesis. Journal of AIDS Research 17, 7-13, 2015.

 

116. Okamoto M, Miyazawa T, Morikawa S, Ono F, Nakamura S, Sato E, Yoshida T, Yoshikawa R, Sakai K, Mizutani T, Nagata N, Takano J, Okabayashi S, Hamano M, Fujimoto K, Nakaya T, Iida T, Horii T, Miyabe-Nishiwaki T, Watanabe A, Kaneko A, Saito A, Matsui A, Hayakawa T, Suzuki J, Akari H, Matsuzawa T, Hirai H: Emergence of infectious malignant thrombocytopenia in Japanese macaques (Macaca fuscata) by SRV-4 after transmission to a novel host. Scientific Reports 5, 8850, 2015.

 

115. Saito A, Kono K, Kawamoto Y, Higashino A, Suzuki S, Yoshida T, Torii R, Yasutomi Y, Shioda T, Nakayama EE, Akari H: Diversity of antiretroviral host factor trim5 gene in macaque monkeys: genetic information for establishment of HIV-1 primate model. Journal of AIDS Research 16, 28-36, 2014.

 

114. Fujie Y, Fusaki N, Katayama T, Hamasaki M, Soejima Y, Soga M, Ban H, Hasegawa M, Yamashita S, Kimura S, Suzuki S, Matsuzawa T, Akari H, Era T: New type of Sendai virus vector provides transgene-free iPS cells derived from chimpanzee blood. PLoS ONE 9, e113052, 2014. 

 

113. Shimoda H, Saito A, Noguchi K, Terada Y, Kuwata R, Akari H, Takasaki T, Maeda K: Seroprevalence of Japanese encephalitis virus infection in captive Japanese macaques (Macaca fuscata). Primates 55, 441-445, 2014.

 

112. Naruse TK, Akari H, Matano T, Kimura A: Divergence and diversity of ULBP2 genes in rhesus and cynomolgus macaques. Immunogenetics 66, 161-170, 2014.

 

111. Moi ML, Takasaki T, Omatsu T, Nakamura S, Katakai Y, Ami Y, Yuriko S, Saijo M, Akari H, Kurane I: Demonstration of marmosets (Callithrix jacchus) as a non-human primate model for secondary dengue virus infection: high levels of viremia and serotype cross-reactive antibody responses consistent with secondary infection of humans.  Journal of General Virology 95, 591-600, 2014.

 

110. Miura M, Yasunaga J, Tanabe J, Sugata K, Zhao T, Ma G, Miyazato P, Ohshima K, Kaneko A, Watanabe A, Saito A, Akari H, Matsuoka M: Characterization of simian T-cell leukemia virus type 1 in naturally infected Japanese macaques as a model of HTLV-1 infection. Retrovirology 10, 118, 2013.

109. Nomaguchi M, Yokoyama M, Kono K, Nakayama EE, Shioda T, Doi N, FujiwaraS, Saito A, Akari H, Miyakawa K, Ryo A, Ode H, Iwatani Y, Miura T, Igarashi T, Sato H, Adachi A: Generation of rhesus macaque-tropic HIV-1clones that are resistant to major anti-HIV-1 restriction factors. Journal of Virology 87, 11447-11461, 2013. (Epub Aug 21, 2013)

108. Yoshida T, Suzuki S, Iwasaki Y, Kaneko A, Saito A, Enomoto Y, Higashino A, Watanabe A, Suzuki J, Inoue K, Kuroda T, Takada M, Ito R, Ito M, Akari H: Efficient in vivo depletion of CD8+ T lymphocytes in common marmosets by novel CD8 monoclonal antibody administration. Immunology Letters 154, 12-17, 2013. (Epub Aug 19, 2013)

107. Saito A, Akari H: Macaque-tropic human immunodeficiency virus type 1 (HIV-1mt): Break out of the host factors. Frontiers in Microbiology 4, 187, 2013. (Epub June 20, 2013)

106. Moi ML, Omatsu T, Hirayama T, Nakamura S, Katakai Y, Yoshida T, Saito A, Tajima S, Ito M, Takasaki T, Akari H, Kurane I: Presence of viral genome in urine and development of hematuria and pathological changes in kidneys in common marmoset (Callithrix jacchus) after inoculation with dengue virus. Pathogens 2, 357-363, 2013.

105. Saito A, Nomaguchi M, Kono K, Iwatani Y, Yokoyama M, Yasutomi Y, Sato H, Shioda T, Sugiura W, Matano T, Adachi A, Nakayama EE, Akari H: TRIM5 genotypes in cynomolgus monkeys primarily influence inter-individual diversity in susceptibility to monkey-tropic human immunodeficiency virus type 1. Journal of General Virology 94, 1318-1324, 2013. (Epub March 13, 2013)

104. Yoshida T, Omatsu T, Saito A, Katakai Y, Iwasaki Y, Kurosawa T, Hamano M, Higashino A, Nakamura S, Takasaki T, Yasutomi Y, Kurane I, Akari H: Dynamics of cellular immune responses in the acute phase of dengue virus infection. Archives of Virology 158, 1209-1220, 2013. (Epub Feb 5, 2013)

103. Nomaguchi M, Doi N, Fujiwara S, Saito A, Akari H, Nakayama EE, Shioda T, Yokoyama M, Sato H, Adachi A: Systemic biological analysis of the mutations in two distinct HIV-1mt genomes occurred during replication in macaque cells. Microbes and Infection 15, 319-28, 2013. (Epub Feb 4, 2013)

102. Nomaguchi M, Yokoyama M, Kono K, Nakayama EE, Shioda T, Saito A, Akari H, Yasutomi Y, Matano T, Sato H, Adachi A: Gag-CA Q110D mutation elicits TRIM5-independent enhancement of HIV-1mt replication in macaque cells. Microbes and Infection 15, 56-65, 2013. (Epub Nov 1, 2012)

101. Kooriyama T, Okamoto M, Yoshida T, Nishida T, Tsubota T, Saito A, Tomonaga M, Matsuzawa T, Akari H, Nishimura H, Miyabe-Nishiwaki T: Epidemiological study of zoonoses derived from humans in captive chimpanzees. Primates 54, 89-98, 2013. (Epub Aug 14, 2012)

100. Saito A, Kawamoto Y, Higashino A, Yoshida T, Ikoma T, Suzaki Y, Ami Y, Shioda T, Nakayama EE, Akari H: Allele Frequency of Antiretroviral Host Factor TRIMCyp in Wild-caught Cynomolgus Macaques (Macaca fascicularis). Frontiers in Microbiology 3, 314, 2012. (Epub Aug 30, 2012)

99. Omatsu T, Moi ML, Takasaki T, Nakamura S, Katakai Y, Tajima S, Ito M, Yoshida T, Saito A, Akari H, Kurane I: Changes in hematological and serum biochemical parameters in common marmosets (Callithrix jacchus) after inoculation with dengue virus. Journal of Medical Primatology 41, 289-296, 2012. (Epub Jul 9, 2012)

98. Ohtani H, Naruse TK, Iwasaki Y, Akari H, Ishida T, Matano T, Kimura A: Lineage-specific evolution of T-cell immunoglobulin and mucin domain 1 gene in the primates. Immunogenetics 64, 669-678, 2012. (Epub Jun 19, 2012)

97. Iijima S, Lee Y-J, Ode H, Arold ST, Kimura N, Yokoyama M, Sato H, Tanaka Y, Strebel K, Akari H: A non-canonical mu-1A-binding motif in the N-terminus of HIV-1 Nef determines its activity to down-regulate MHC-I in T lymphocytes. Journal of Virology 86, 3944-51, 2012. (Epub Feb 1, 2012)

96. Saito A, Kono K, Nomaguchi M, Yasutomi Y, Adachi A, Shioda T, Akari H, Nakayama EE: Geographic, genetic and functional diversity of antiretroviral host factor TRIMCyp in Cynomolgus macaque (Macaca fascicularis). Journal of General Virology 93, 594-602, 2012. (Epub Nov 23, 2011)

95. Takeuchi H, Ishii H, Kuwano T, Inagaki N, Akari H, Matano T: Host cell species-specific effect of cyclosporine A on simian immunodeficiency virus replication. Retrovirology 9, 3, 2012.

94. Yoshida T, Omatsu T, Saito A, Katakai Y, Iwasaki Y, Kurosawa T, Hamano M, Nakamura S, Takasaki T, Yasutomi Y, Kurane I, Akari H: CD16 positive natural killer cells play a limited role against primary dengue virus infection in tamarins. Archives of Virology 157, 363-368, 2012. (Epub Dec 3, 2011)

93. Saito Y, Naruse TK, Akari H, Matano T, Kimura A: Diversity of MHC class I haplotypes in cynomolgus macaques. Immunogenetics 64, 131-141, 2012. (Epub Sep 1, 2011)

92. Iwasaki Y, Mori K, Ishii K, Maki N, Iijima S, Yoshida T, Okabayashi S, Katakai Y, Lee Y-J, Saito A, Fukai H, Kimura N, Ageyama N, Yoshizaki S, Suzuki T, Yasutomi Y, Miyamura T, Kannagi M, Akari H: Long-term persistent GBV-B infection and development of a progressive chronic hepatitis C–like disease in marmosets. Frontiers in Microbiology 2, 240, 2011. doi: 10.3389/fmicb.2011.00240

91. Omatsu T, Moi ML, Hirayama T, Takasaki T, Nakamura S, Tajima S, Ito M, Yoshida T, Saito A, Katakai Y, Akari H, Kurane I: Common marmoset (Callithrix jacchus) as a primate Model of dengue virus infection: development of high levels of viremia and demonstration of protective immunity. Journal of General Virology 92, 2272-2280, 2011. (Epub June 22, 2011)

90. Naruse TK, Okuda Y, Mori K, Akari H, Matano T, Kimura A: ULBP4/RAET1E is highly polymorphic in the Old World monkey. Immunogenetics 63, 501-509, 2011. (Epub May 7, 2011)

89. Ito M, Katakai Y, Ono F, Akari H, Mukai RZ, Takasaki T, Kotaki A, Kurane I: Serotype-specific and cross-reactive neutralizing antibody responses in cynomolgus monkeys after infection with multiple dengue virus serotypes. Archives of Virology156, 1073-1077, 2011. (Epub March 16, 2011)

88. Ohtani H, Nakajima T, Akari H, Ishida T, Kimura A: Molecular evolution of immunoglobulin superfamily genes in primates. Immunogenetics 63, 417-428, 2011. (Epub March 10, 2011)

87. Saito A, Nomaguchi M, Iijima S, Kuroishi A, Yoshida T, Lee YJ, Hayakawa T, Kono K, Nakayama EE, Shioda T, Yasutomi Y, Adachi A, Matano T, Akari H: Improved capacity of a monkey-tropic HIV-1 derivative to replicate in cynomolgus monkeys with minimal modifications. Microbes and Infection13, 58-64, 2011. (Epub Oct 15, 2010)

86. Yoshida T, Saito A, Iwasaki Y, Iijima S, Kurosawa T, Katakai Y, Yasutomi Y, Reimann KA, Hayakawa T, Akari H: Characterization of natural killer cells in tamarins: a technical basis for studies of innate immunity. Frontiers in Microbiology 1, 128, 2010.

85. Naruse TK, Chen Z, Yanagida R, Yamashita T, Saito Y, Mori K, Akari H,Yasutomi Y, Miyazawa M, Matano T, Kimura A: Diversity of MHC class I genes in Burmese-origin rhesus macaques. Immunogenetics 62, 601-611, 2010. (Epub July 17, 2010)

84. Matsumoto Y, Miura T, Akari H, Goto Y, Haga T: Peripheral blood CD4 CD8 double-positive T cells of rhesus macaques become vulnerable to Simian Immunodeficiency Virus by in vitro stimulation due to the induction of CCR5. Journal of Veterinary Medical Science 72, 1057-1061, 2010. (Epub March 12, 2010)